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International Journal of Antimicrobial Agents

SARS-CoV-2 was already spreading in France in late December 2019
Available online 3 May 2020, 106006
https://www.sciencedirect.com/scien...924857920301643

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During the study period, 14 (24%) of 58 patients admitted for ILI were included in the current analysis (Table 1). One sample taken from a 42-year-old unemployed male born in Algeria who had lived in France for many years was positive. His last foreign travel was to Algeria in August 2019. One of his children presented with ILI prior to the onset of his symptoms. His medical history included asthma and type II diabetes mellitus. He presented to the emergency ward on 27 December 2019 with haemoptysis, cough, chest pain, headache and fever, evolving for 4 days. Initial examination was unremarkable and chest computed tomography (CT) imaging revealed bilateral pulmonary ground-glass opacities in the inferior lobes.

Here we report an observation of a SARS-CoV-2-infected patient 1 month before the first reported cases in France. On admission, the patient presented clinical signs and radiological patterns frequently observed previously in Chinese [9] and Italian [10] cohorts. Identifying the first infected patient is of great epidemiological interest as it changes dramatically our knowledge regarding SARS-CoV-2 and its spread in the country. Moreover, the absence of a link with China and the lack of recent foreign travel suggest that the disease was already spreading among the French population at the end of December 2019.


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